If you want to mine in zeroes you should enable and use real time local monitor. This function generates Emergency Warp Out event (EWO) if any character with disallowed standing appears in local. This function requires expanded local window and you must set this window expanded during first run if you check Shared Settings->First Run Wizard Settings->Expand PnP and Local Chat as described here. Local monitor will also generate EWO if the number of characters in local chat window does not fit into local chat window height. If you want to disable EWO in this situation, untick 'EWO if Too Many Chars in Local' checkbox. This way you can use local monitor in high sec, where a lot of players in local. If you will not expand local chat window, but activate real time local monitor with EWO if too many chars in local, bot will never leave POS or station.

'Local Cleared Delay' - set this time to return to regular work after local is cleared. Dont make this time too short.

'Avoid standing icons group' - here you can define what standing icons count as hostile and avoid.

'Grouping' is an exchange of information between several clients on the same computer. Dont confuse grouping and fleeting. Fleeting is for fleet bonuses, grouping is for organized actions. If you want them to act as a group enable one of the following options:

• 'Local Check Grouping' - clients will exchange an information about local state and generate EWO of the group at nearly the same time.
• 'Fight Mode Grouping' - if one client start fight with NPC, whole group start fight. This may help you to kill BS sized NPC faster if you have several miners at the same location.
• If you want to use a tank check 'Group Tank Use' option. Each member of a group with selected tank will not warp to belts on its own, but when tank confirms that all NPCs aggroed to the tank. This might take up to 30 minutes if no NPCs present in the belt when tank warped to it. It is important to have the same set of bookmarks for each member of the tank group. Names of the bookmarks may differ, only position of the bookmark in people and places is important. If you do this, group members will able to warp to correct belt with the tank. Please make sure that no PC hunters kill your NPCs, there are no additional checks if NPC still present in the belt after tank installation.
• 'Selected Tank'. The tank is a hulk with good fit and skills which warps to belt and waiting while all NPCs aggro to it. After all NPC aggro collected, tank sends command to its group to warp in. Selected tank should not transport its ore, use jettison container function. If you dont need to keep aggro of all NPC to particular ship but want to tell your miners or remote hauler to warp and work in the same belt, check 'Dont Check NPC (for high sec.)'. All miners may not be in the same fleet. "Fleet" is for bonuses, "tank group" is for synchronous actions. Update: since NPCs started to switch aggro, the only role of a selected tank is to define location where to warp to other miners or looter.
• 'Group Synchronization' - group synchronization is a mode when each client is waiting for other clients to do the next task synchronously. The place where group will wait for other group members is defined by position of a Barrier function in algorithm and default positions are: 1) before warping to belt, 2) before PI work start, 3) after PI work start. You dont need this function despite very particular case when you want to restart extractors on planets in zeroes for several clients and want to have all miners at POS location when you start this work. Group synchronization has nothing to do with selection of the belt where to warp. Use group tank option instead.

'Use Arrays' is the only used if you mine to POS. If you have compression or ship assembly array you may unload ore to this structure rather then into corporate/personal hangar. Arrays have more free space (15+ freighters). With new EVE inventory you cannot define division where to unload ore at POS hangar or array. But you can define this position during first run wizard manually. After bot finished resizing and reposition of the hangar window pause bot with control+p, select required division and unpause bot to finish first run wizard.